© Copyright 2002 by Dietrich Klinghardt M.D., Ph.D., USA.
(Explore Issue: Volume 12, Number 2)
American Academy of Neural Therapy and Institute of Neurobiology (Bellevue, WA, USA)
Institute for Neurobiologie (Stuttgart, Germany)
Academy for Balanced NeuroBiology Ltd (London, United Kingdom)
This lecture was presented by Dietrich Klinghardt M.D., Ph.D. at the Jean Piaget Department at the University of Geneva, Switzerland Oct.2002 to physicians and dentists from Europe, Israel, several Arab countries and Asia.
What are Neurotoxins?
Neurotoxins are substances attracted to the mammalian nervous system. They are absorbed by nerve endings and travel inside the neuron to the cell body. On their way they disrupt vital functions of the nerve cell, such as axonal transport of nutrients, mitochondrial respiration and proper DNA transcription. The body is constantly trying to eliminate neurotoxins via the available exit routes: the liver, kidney, skin and exhaled air. Detox mechanisms include acetylation, sulfation, glucuronidation, oxidation and others. The liver is most important in these processes. Here most elimination products are expelled with the bile into the small intestine and should leave the body via the digestive tract. However, because of the lipophilic/neurotropic nature of the neurotoxins, most are reabsorbed by the abundant nerve endings of the enteric nervous system (ENS) in the intestinal wall. The ENS has more neurons than the spinal cord. From the moment of mucosal uptake the toxins can potentially take 4 different paths: